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For individuals with severe insect sting allergies, a single sting can trigger a life-threatening reaction known as anaphylaxis. Fortunately, a highly effective treatment called venom immunotherapy (VIT) is available—and at WinnMed, patients can receive this specialized care under the expert guidance of Michael D’Netto, M.D., a Mayo Clinic Health System board-certified Allergist and Immunologist.

Venom immunotherapy is a long-term treatment that works by gradually desensitizing the immune system to insect venom. It involves regular injections of purified venom extracts from stinging insects such as honeybees, wasps, hornets, and yellow jackets. Over time, the body builds tolerance, significantly reducing the risk of a severe allergic reaction with future stings 

“Venom immunotherapy is more than just symptom management—it’s a preventive therapy that can save lives. This is done by essentially re-programming the immune system to no longer react to venoms in an allergic manner,” says Dr. D’Netto. “For patients who’ve experienced anaphylaxis due to one of the aforementioned stinging insects, this treatment offers peace of mind and long-term protection.”

The treatment typically spans 3 to 5 years, with a build-up phase followed by a maintenance phase. Studies show that venom immunotherapy is 95–98% effective in preventing systemic allergic reactions to future stings 

Dr. D’Netto begins with a comprehensive allergy evaluation, including skin or blood testing, to confirm venom sensitivity. From there, he develops a personalized treatment plan tailored to each patient’s needs and risk factors.

If you or a loved one has experienced a serious reaction to an insect sting, talk to your provider about a referral to Dr. D’Netto. Venom immunotherapy could be the key to a safer, more confident life outdoors.

Make an appointment

Dr. D’Netto is accepting new patients at WinnMed in Decorah.  Call WinnMed at 563-382-2911 or request an appointment online through WinnMed’s online portal, MyChart.

Expert Advice from Michael D’Netto, M.D.

If you’re struggling with persistent allergy symptoms despite medications or avoidance strategies, allergy shots—also known as subcutaneous immunotherapy (SCIT)—may be a game-changing option. But are they right for you?

“Allergy shots are the only treatment that can actually retrain the immune system to stop overreacting to allergens,” says Michael D’Netto, M.D., a Mayo Clinic Health System board-certified Allergist and Immunologist at WinnMed in Decorah. “Unlike medications, they don’t just mask symptoms—they address the root cause.”

Pros of Allergy Shots

• Long-Term Relief: Allergy shots can reduce or eliminate symptoms for years, even after treatment ends.
• Fewer Medications: Many patients are able to reduce or stop allergy medications over time.
• Prevention of New Allergies: Immunotherapy may prevent the development of new allergies and reduce the risk of asthma, particularly in children.
• Customized Treatment: Shots are tailored to your specific allergens, based on allergy testing.

Cons of Allergy Shots

• Time Commitment: Treatment typically lasts 3 to 5 years, with weekly injections during the build-up phase and monthly injections during the maintenance phase.
• Possible Reactions: Mild side effects include redness or swelling at the injection site. Rarely, more serious reactions like anaphylaxis can occur, which is why patients are monitored for 30 minutes after each shot.
• Not for Food Allergies: Allergy shots are effective for environmental allergens and insect stings, but not for food allergies.

Is It Right for You?

“If your allergies are affecting your quality of life, and medications aren’t enough, allergy shots may be the best long-term solution,” Dr. D’Netto explains. “We’ll work together to determine if you’re a good candidate.”

Make an appointment

Dr. D’Netto is accepting new patients at WinnMed in Decorah.  Call WinnMed at 563-382-2911 or request an appointment online through WinnMed’s online portal, MyChart.